Basic Information
| Drug ID | DDPD00284 |
|
| Drug Name | Acarbose | |
| Molecular Weight | 645.608 | |
| Molecular Formula | C25H43NO18 | |
| CAS Number | 56180-94-0 | |
| SMILES | [H]C(=O)[C@H](O)[C@@H](O)[C@]([H])(O[C@@]1([H])O[C@H](CO)[C@@]([H])(O[C@H]2O[C@H](C)[C@@H](N[C@@]3([H])C=C(CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)CO | |
| External Links | ||
| DRUGBANK | DB00284 | |
| PubChem Compound | 9811704 | |
| PDR | 1315 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -6.8 | - | -6.8 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 2.0 | % | <2 | % | PO, oral; | DRUGBANK |
| T Max | 1.0 | h | 1 | h | PO, oral; | DRUGBANK |
| Clearance | 0.13 | L/h/kg | 2.2 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.32 | L/kg | 0.32 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.0 | h | 2 | h | normal,healthy; | DRUGBANK | Half-life | 2.7 | h | 2.7 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 150.0 | mg/day | 150 | mg/day | PO, oral | Precose | acarbose | PDR |
| Max dose for adults | 300.0 | mg/day | 300 | mg/day | PO, oral | Precose | acarbose | PDR |
| Max dose for geriatric | 150.0 | mg/day | 150 | mg/day | PO, oral | Precose | acarbose | PDR |
| Max dose for geriatric | 300.0 | mg/day | 300 | mg/day | PO, oral | Precose | acarbose | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1