Basic Information

Drug ID DDPD00278 ...
Drug Name Argatroban
Molecular Weight 508.64
Molecular Formula C23H36N6O5S
CAS Number 74863-84-6
SMILES C[C@@H]1CCN([C@H](C1)C(O)=O)C(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)C1=CC=CC2=C1NCC(C)C2
External Links
DRUGBANK DB00278
PubChem Compound 152951
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 1.0 - 1.0 - DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 100.0 % 100.0 % intravenous injection, IV; DRUGBANK
Clearance 5.1 L/h/kg 5.1 L/kg/h intravenous infusion, IV in drop; DRUGBANK
Clearance 0.30 L/h/kg 5 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.17 L/kg 174.0 ml/kg DRUGBANK
Volume of Distribution 12.2 L 12.18 L adults; DRUGBANK
Volume of Distribution 0.17 L/kg 0.17 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 0.75 h 39-51 min DRUGBANK
Half-life 0.40 h 0.4 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 65.0 % 65 % Faeces excretion; DRUGBANK
Eliminate Route 22.0 % 22 % Urinary excretion; DRUGBANK
Protein Binding 54.0 % 54 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1