DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD00276
Drug Name	Amsacrine
Molecular Weight	393.459
Molecular Formula	C21H19N3O3S
CAS Number	51264-14-3
SMILES	COC1=C(NC2=C3C=CC=CC3=NC3=CC=CC=C23)C=CC(NS(C)(=O)=O)=C1
External Links
	DRUGBANK	DB00276
	T3DB	T3D4674
	PubChem Compound	2179

Experimental Physicochemical Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Reference
Log P	3.8	-	3.8	-	DRUGBANK
Melting Point	235.0	℃	235	℃	PhysProp
Water Solubility	1000.0	mg/L	<1	mg/ml	DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
Clearance	0.26	L/h/kg	4.3	ml/min/kg	intravenous injection, IV; human, homo sapiens;	Human Intravenous Pharmacokinetic Dataset
Volume of Distribution	1.6	L/kg	1.6	L/kg	intravenous injection, IV; human, homo sapiens;	Human Intravenous Pharmacokinetic Dataset
Half-life	8.5	h	8-9	h		DRUGBANK
Half-life	4.7	h	4.7	h	intravenous injection, IV; human, homo sapiens;	Human Intravenous Pharmacokinetic Dataset
Protein Binding	97.0	%	96-98	%		DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1