Basic Information

Drug ID DDPD00263 ...
Drug Name Sulfisoxazole
Molecular Weight 267.304
Molecular Formula C11H13N3O3S
CAS Number 127-69-5
SMILES CC1=NOC(NS(=O)(=O)C2=CC=C(N)C=C2)=C1C
External Links
DRUGBANK DB00263
PubChem Compound 5344
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 1.01 - 1.01 - HANSCH,C ET AL. (1995)
Melting Point 191.0 191 PhysProp
Water Solubility 300.0 mg/L 300 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)
pKa 5.0 - 5 - DRUGBANK
Log S -2.91 - -2.91 - ADME Research, USCD

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.0180 L/h/kg 0.3 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.17 L/kg 0.17 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 7.4 h 7.4 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Toxicity LD50 6800.0 mg/kg 6800.0 mg/kg PO, oral; mouse; DRUGBANK
Eliminate Route 97.0 % 97 % Urinary excretion; PO, oral; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1