Basic Information
| Drug ID | DDPD00263 |
|
| Drug Name | Sulfisoxazole | |
| Molecular Weight | 267.304 | |
| Molecular Formula | C11H13N3O3S | |
| CAS Number | 127-69-5 | |
| SMILES | CC1=NOC(NS(=O)(=O)C2=CC=C(N)C=C2)=C1C | |
| External Links | ||
| DRUGBANK | DB00263 | |
| PubChem Compound | 5344 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.01 | - | 1.01 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 191.0 | ℃ | 191 | ℃ | PhysProp |
| Water Solubility | 300.0 | mg/L | 300 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 5.0 | - | 5 | - | DRUGBANK |
| Log S | -2.91 | - | -2.91 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.0180 | L/h/kg | 0.3 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.17 | L/kg | 0.17 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 7.4 | h | 7.4 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 6800.0 | mg/kg | 6800.0 | mg/kg | PO, oral; mouse; | DRUGBANK |
| Eliminate Route | 97.0 | % | 97 | % | Urinary excretion; PO, oral; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1