Basic Information
| Drug ID | DDPD00259 |
|
| Drug Name | Sulfanilamide | |
| Molecular Weight | 172.205 | |
| Molecular Formula | C6H8N2O2S | |
| CAS Number | 63-74-1 | |
| SMILES | NC1=CC=C(C=C1)S(N)(=O)=O | |
| External Links | ||
| DRUGBANK | DB00259 | |
| PubChem Compound | 5333 | |
| PDR | 685 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.62 | - | -0.62 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 165.5 | ℃ | 165.5 | ℃ | PhysProp |
| Water Solubility | 7500.0 | mg/L | 7500 | mg/L | MERCK INDEX 1976) |
| pKa | 10.6 | - | 10.6 | - | SERJEANT,EP & DEMPSEY,B (1979) |
| Log S | -1.36 | - | -1.36 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Toxicity LD50 | 3700.0 | mg/kg | 3700.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 621.0 | mg/kg | 621.0 | mg/kg | intravenous injection, IV; mouse; | DRUGBANK | Toxicity LD50 | 1300.0 | mg/kg | 1300.0 | mg/kg | PO, oral; rabbit; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 2.0 | appLicatorfuL/day | 2 | appLicatorfuL/day | Vaginal Administration | AVC | sulfanilamide | PDR |
| Max dose for adults | 2.0 | suppositories/day | 2 | suppositories/day | Vaginal Administration | AVC | sulfanilamide | PDR |
| Max dose for elderly | 2.0 | applicatorful/day | 2 | applicatorful/day | Vaginal Administration | AVC | sulfanilamide | PDR |
| Max dose for elderly | 2.0 | suppositories/day | 2 | suppositories/day | Vaginal Administration | AVC | sulfanilamide | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1