Basic Information
| Drug ID | DDPD00257 |
|
| Drug Name | Clotrimazole | |
| Molecular Weight | 344.837 | |
| Molecular Formula | C22H17ClN2 | |
| CAS Number | 23593-75-1 | |
| SMILES | ClC1=CC=CC=C1C(N1C=CN=C1)(C1=CC=CC=C1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00257 | |
| T3DB | T3D2729 | |
| PubChem Compound | 2812 | |
| PDR | 1424 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.5 | - | 0.5 | - | https://www.researchgate.net/publication/262605568_Clotrimazole_as_a_pharmaceutical_Past_present_and_future |
| Melting Point | 148.0 | ℃ | 148 | ℃ | MSDS |
| Water Solubility | 0.49 | mg/L | 0.49 | mg/L | http://www.ijpsonline.com/articles/improvement-of-solubility-and-dissolution-properties-of-clotrimazole-by-solid-dispersions-and-inclusion-complexes.pdf |
| pKa | 4.1 | - | 4.1 | - | http://www.ijpsonline.com/articles/improvement-of-solubility-and-dissolution-properties-of-clotrimazole-by-solid-dispersions-and-inclusion-complexes.pdf |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Toxicity LD50 | 708.0 | mg/kg | 708.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 445.0 | mg/kg | 445.0 | mg/kg | Intraperitoneal, IP; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 761.0 | mg/kg | 761.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 108.0 | mg/kg | 108.0 | mg/kg | Intraperitoneal, IP; mouse; | DRUGBANK |
| Toxicity LDLo | 10000.0 | mg/kg | 10.0 | g/kg | subcutaneous injection, SC; Rattus, Rat; | DRUGBANK | Toxicity LDLo | 10000.0 | mg/kg | 10.0 | g/kg | subcutaneous injection, SC; mouse; | DRUGBANK |
| Protein Binding | 98.0 | % | 98 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1