Basic Information
| Drug ID | DDPD00251 |
|
| Drug Name | Terconazole | |
| Molecular Weight | 532.462 | |
| Molecular Formula | C26H31Cl2N5O3 | |
| CAS Number | 67915-31-5 | |
| SMILES | CC(C)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1 | |
| External Links | ||
| DRUGBANK | DB00251 | |
| PubChem Compound | 441383 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.5 | - | 4.5 | - | DRUGBANK |
| Melting Point | 126.3 | ℃ | 126.3 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 6.5 | % | 5-8 | % | Vaginal Administration; hysterectomized; | DRUGBANK | Bioavailability | 14.0 | % | 12-16 | % | Vaginal Administration; tubal ligations; | DRUGBANK |
| Half-life | 6.9 | h | 6.9(4.0-11.3) | h | DRUGBANK | |
| Toxicity LD50 | 1741.0 | mg/kg | 1741.0 | mg/kg | PO, oral; male rat; | DRUGBANK | Toxicity LD50 | 849.0 | mg/kg | 849.0 | mg/kg | PO, oral; female rat; | DRUGBANK |
| Eliminate Route | 44.0 | % | 32-56 | % | Urinary excretion; PO, oral; | DRUGBANK | Eliminate Route | 49.5 | % | 47-52 | % | Faeces excretion; PO, oral; | DRUGBANK |
| Protein Binding | 94.9 | % | 94.9 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1