Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
C Max |
2100.0 |
ng/ml |
2.1 |
mg/L |
PO, oral; |
DRUGBANK |
T Max |
2.0 |
h |
~2 |
h |
PO, oral; |
DRUGBANK |
Metabolic |
100.0 |
% |
~100 |
% |
Liver metabolism; |
DRUGBANK |
Volume of Distribution |
0.80 |
L/kg |
~0.8 |
L/kg |
|
DRUGBANK |
Half-life |
35.0 |
h |
~35 |
h |
elimination half-life; |
DRUGBANK |
Half-life |
61.0 |
h |
61(35-88) |
h |
elimination half-life; normal,healthy; Drug combination; |
DRUGBANK |
Toxicity TDLo |
400.0 |
mg/kg |
400.0 |
mg/kg |
PO, oral; Female, women; |
DRUGBANK |
Toxicity TDLo |
160.0 |
mg/kg |
160.0 |
mg/kg |
subcutaneous injection, SC; Rattus, Rat; |
DRUGBANK |
Toxicity Lethal Dose |
2000.0 |
mg |
2.0 |
g |
adults; |
DRUGBANK |
Eliminate Route |
73.5 |
% |
59-88 |
% |
Urinary excretion; |
DRUGBANK |
Eliminate Route |
3.6 |
% |
~3.6 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Protein Binding |
45.0 |
% |
45 |
% |
plasma proteins; high protein binding; |
DRUGBANK |