Basic Information
| Drug ID | DDPD00237 |
|
| Drug Name | Butabarbital | |
| Molecular Weight | 212.2456 | |
| Molecular Formula | C10H16N2O3 | |
| CAS Number | 125-40-6 | |
| SMILES | CCC(C)C1(CC)C(=O)NC(=O)NC1=O | |
| External Links | ||
| DRUGBANK | DB00237 | |
| T3DB | T3D2721 | |
| PubChem Compound | 2479 | |
| PDR | 1383 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.65 | - | 1.65 | - | WONG,O & MCKEOWN,RH (1988) |
| Melting Point | 166.5 | ℃ | 166.5 | ℃ | PhysProp |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 100.0 | h | 100 | h | terminal half-life; | DRUGBANK |
| Eliminate Route | 4.0 | % | 3-5 | % | Urinary excretion; dog; Unchanged drug; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for infants | 6.0 | mg/kg/dose | 6 | mg/kg/dose | PO, oral | Butisol Sodium | butabarbital sodium | PDR |
| Max dose for children | 6.0 | mg/kg/dose | 6 | mg/kg/dose | PO, oral | Butisol Sodium | butabarbital sodium | PDR |
| Max dose for children | 100.0 | mg/dose | 100 | mg/dose | PO, oral | Butisol Sodium | butabarbital sodium | PDR |
| Max dose for adolescents | 6.0 | mg/kg/dose | 6 | mg/kg/dose | PO, oral | Butisol Sodium | butabarbital sodium | PDR |
| Max dose for adolescents | 100.0 | mg/dose | 100 | mg/dose | PO, oral | Butisol Sodium | butabarbital sodium | PDR |
| Max dose for adults | 120.0 | mg/day | 120 | mg/day | PO, oral | Butisol Sodium | butabarbital sodium | PDR |
| Max dose for geriatric | 120.0 | mg/day | 120 | mg/day | PO, oral | Butisol Sodium | butabarbital sodium | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1