Basic Information

Drug ID DDPD00234 ...
Drug Name Reboxetine
Molecular Weight 313.397
Molecular Formula C19H23NO3
CAS Number 71620-89-8
SMILES [H][C@@](OC1=CC=CC=C1OCC)(C1=CC=CC=C1)[C@@]1([H])CNCCO1
External Links
DRUGBANK DB00234
T3DB T3D2720
PubChem Compound 127151

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 3.1 - 3.1 - DRUGBANK
Melting Point 170.5 170-171 DRUGBANK
Water Solubility 8000.0 mg/L 8 mg/ml DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.0492 L/h/kg 0.82 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.65 L/kg 0.65 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 12.5 h 12.5 h DRUGBANK
Half-life 10.0 h 10 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 98.0 % 98 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1