Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00229 ...
Drug Name Cefotiam
Molecular Weight 525.628
Molecular Formula C18H23N9O4S3
CAS Number 61622-34-2
SMILES [H][C@]12SCC(CSC3=NN=NN3CCN(C)C)=C(N1C(=O)[C@H]2NC(=O)CC1=CSC(N)=N1)C(O)=O
External Links
DRUGBANK DB00229
PubChem Compound 43708

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -2.1 - -2.1 - DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 60.0 % 60.0 % IM,intramuscular injection; DRUGBANK
Clearance 0.35 L/h/kg 5.8 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.26 L/kg 0.26 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.0 h ~1 h DRUGBANK
Half-life 0.84 h 0.84 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 40.0 % 40 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1