DETAILS

Property Name	Property Value	Unit	Raw Value	Raw Unit	Reference
Log P	3.356	-	3.356	-	'MSDS'
Melting Point	163.5	℃	163-164	℃	'MSDS'
pKa	7.1	-	7.1	-	'FDA label'

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Factor	Reference
Bioavailability	80.0	%	>80	%			DRUGBANK
T Max	1.0	h	1	h	PO, oral; food;	food → ;	DRUGBANK
Metabolic	80.0	%	80	%	Liver metabolism; Inactive metabolite;		DRUGBANK
Metabolic	9.0	%	9	%			DRUGBANK
Metabolic	11.0	%	11	%			DRUGBANK
Volume of Distribution	0.20	L/kg	0.2	L/kg			DRUGBANK
Half-life	3.5	h	3.5	h			DRUGBANK
Toxicity LD50	5000.0	mg/kg	5.0	g/kg	PO, oral; Rattus, Rat;		DRUGBANK
Eliminate Route	75.0	%	70-80	%	Faeces excretion;		DRUGBANK
Eliminate Route	25.0	%	20-30	%	Urinary excretion;		DRUGBANK
Protein Binding	99.0	%	>99	%	plasma proteins;		DRUGBANK

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Brand Name	Component	Reference
Max dose for adults	10.0	mg/day	10	mg/day	PO, oral;intravenous injection, IV;	Demadex	torsemide	PDR
Max dose for adults	200.0	mg	200	mg	PO, oral;intravenous injection, IV;	Demadex	torsemide	PDR
Max dose for adults	40.0	mg	40	mg	PO, oral;intravenous injection, IV;	Demadex	torsemide	PDR
Max dose for elderly	10.0	mg/day	10	mg/day	PO, oral;intravenous injection, IV;	Demadex	torsemide	PDR
Max dose for elderly	200.0	mg	200	mg	PO, oral;intravenous injection, IV;	Demadex	torsemide	PDR
Max dose for elderly	40.0	mg	40	mg	PO, oral;intravenous injection, IV;	Demadex	torsemide	PDR

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1