| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Factor |
Reference |
| Bioavailability |
93.0 |
% |
93.0 |
% |
PO, oral; food; |
food → ; |
DRUGBANK |
| T Max |
0.50 |
h |
0.5 |
h |
PO, oral; |
|
DRUGBANK |
| Clearance |
23.1 |
L/h |
385.0 |
ml/min |
Renal clearance; |
|
DRUGBANK |
Clearance |
1.7 |
L/h/kg |
27.9 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
0.67 |
L/kg |
0.67 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
3.5 |
h |
~3-4 |
h |
Metabolite; |
|
DRUGBANK |
Half-life |
0.60 |
h |
0.6 |
h |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 |
40.0 |
mg/kg |
~30-50 |
mg/kg |
PO, oral; Rattus, Rat; |
|
DRUGBANK |
Toxicity LD50 |
675.0 |
mg/kg |
~675 |
mg/kg |
PO, oral; mouse; |
|
DRUGBANK |
Toxicity LD50 |
142.5 |
mg/kg |
~125-160 |
mg/kg |
PO, oral; dog; |
|
DRUGBANK |
