Basic Information
| Drug ID | DDPD00185 |
|
| Drug Name | Cevimeline | |
| Molecular Weight | 199.313 | |
| Molecular Formula | C10H17NOS | |
| CAS Number | 107233-08-9 | |
| SMILES | CC1O[C@@]2(CS1)CN1CCC2CC1 | |
| External Links | ||
| DRUGBANK | DB00185 | |
| PubChem Compound | 25137844 | |
| PDR | 1324 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.3 | - | 1.3 | - | DRUGBANK |
| Melting Point | 202.0 | ℃ | 201-203 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.8 | h | 1.5-2 | h | DRUGBANK | |
| Metabolic | 44.5 | % | 44.5 | % | Liver metabolism; | DRUGBANK | Metabolic | 22.3 | % | 22.3 | % | Liver metabolism; | DRUGBANK | Metabolic | 4.0 | % | 4 | % | Liver metabolism; | DRUGBANK |
| Volume of Distribution | 6.0 | L/kg | 6.0 | L/kg | DRUGBANK | |
| Half-life | 5.0 | h | 5±1 | h | DRUGBANK | |
| Eliminate Route | 84.0 | % | 84 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 20.0 | % | <20 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 90.0 | mg/day | 90 | mg/day | PO, oral | Evoxac | cevimeline hydrochloride | PDR |
| Max dose for elderly | 90.0 | mg/day | 90 | mg/day | PO, oral | Evoxac | cevimeline hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1