Basic Information

Drug ID DDPD00180 ...
Drug Name Flunisolide
Molecular Weight 434.4977
Molecular Formula C24H31FO6
CAS Number 3385-03-3
SMILES [H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)CO
External Links
DRUGBANK DB00180
PubChem Compound 82153
PDR 1176
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 1.1 - 1.1 - DRUGBANK
Melting Point 228.0 226-230 American Cyanamid Co.; British Patent 933,867; August 14, 1963.

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.57 L/h/kg 9.5 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 1.1 L/kg 1.08 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.8 h 1.8 h DRUGBANK
Half-life 1.7 h 1.68 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 40.0 % ~40 % PO, oral; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for children 0.64 mg/day 640 mcg/day inhalation, IH Aerospan flunisolide PDR
Max dose for children 100.0 mcg/nostril/day 100 mcg/nostril/day nasal spray Aerospan flunisolide PDR
Max dose for children 0.32 mg/day 320 mcg/day inhalation, IH Aerospan flunisolide PDR
Max dose for children 100.0 mcg/nostril/day 100 mcg/nostril/day nasal spray Aerospan flunisolide PDR
Max dose for adolescents 0.64 mg/day 640 mcg/day inhalation, IH Aerospan flunisolide PDR
Max dose for adolescents 200.0 mcg/nostril/day 200 mcg/nostril/day nasal spray Aerospan flunisolide PDR
Max dose for adolescents 0.64 mg/day 640 mcg/day inhalation, IH Aerospan flunisolide PDR
Max dose for adolescents 100.0 mcg/nostril/day 100 mcg/nostril/day nasal spray Aerospan flunisolide PDR
Max dose for adults 0.64 mg/day 640 mcg/day inhalation, IH Aerospan flunisolide PDR
Max dose for adults 200.0 mcg/nostriL/day 200 mcg/nostriL/day nasal spray Aerospan flunisolide PDR
Max dose for geriatric 0.64 mg/day 640 mcg/day inhalation, IH Aerospan flunisolide PDR
Max dose for geriatric 0.2 mg/day 200 mcg/nostril/day nasal spray Aerospan flunisolide PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1