Drug ID | DDPD00180 |
|
Drug Name | Flunisolide | |
Molecular Weight | 434.4977 | |
Molecular Formula | C24H31FO6 | |
CAS Number | 3385-03-3 | |
SMILES | [H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)CO | |
External Links | ||
DRUGBANK | DB00180 | |
PubChem Compound | 82153 | |
PDR | 1176 | |
Drugs.com | Drugs.com Drug Page |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
---|---|---|---|---|---|
Log P | 1.1 | - | 1.1 | - | DRUGBANK |
Melting Point | 228.0 | ℃ | 226-230 | ℃ | American Cyanamid Co.; British Patent 933,867; August 14, 1963. |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
---|---|---|---|---|---|---|
Clearance | 0.57 | L/h/kg | 9.5 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution | 1.1 | L/kg | 1.08 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Half-life | 1.8 | h | 1.8 | h | DRUGBANK | Half-life | 1.7 | h | 1.68 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Protein Binding | 40.0 | % | ~40 | % | PO, oral; | DRUGBANK |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
---|---|---|---|---|---|---|---|---|
Max dose for children | 0.64 | mg/day | 640 | mcg/day | inhalation, IH | Aerospan | flunisolide | PDR |
Max dose for children | 100.0 | mcg/nostril/day | 100 | mcg/nostril/day | nasal spray | Aerospan | flunisolide | PDR |
Max dose for children | 0.32 | mg/day | 320 | mcg/day | inhalation, IH | Aerospan | flunisolide | PDR |
Max dose for children | 100.0 | mcg/nostril/day | 100 | mcg/nostril/day | nasal spray | Aerospan | flunisolide | PDR |
Max dose for adolescents | 0.64 | mg/day | 640 | mcg/day | inhalation, IH | Aerospan | flunisolide | PDR |
Max dose for adolescents | 200.0 | mcg/nostril/day | 200 | mcg/nostril/day | nasal spray | Aerospan | flunisolide | PDR |
Max dose for adolescents | 0.64 | mg/day | 640 | mcg/day | inhalation, IH | Aerospan | flunisolide | PDR |
Max dose for adolescents | 100.0 | mcg/nostril/day | 100 | mcg/nostril/day | nasal spray | Aerospan | flunisolide | PDR |
Max dose for adults | 0.64 | mg/day | 640 | mcg/day | inhalation, IH | Aerospan | flunisolide | PDR |
Max dose for adults | 200.0 | mcg/nostriL/day | 200 | mcg/nostriL/day | nasal spray | Aerospan | flunisolide | PDR |
Max dose for geriatric | 0.64 | mg/day | 640 | mcg/day | inhalation, IH | Aerospan | flunisolide | PDR |
Max dose for geriatric | 0.2 | mg/day | 200 | mcg/nostril/day | nasal spray | Aerospan | flunisolide | PDR |