Basic Information
| Drug ID | DDPD00176 |
|
| Drug Name | Fluvoxamine | |
| Molecular Weight | 318.34 | |
| Molecular Formula | C15H21F3N2O2 | |
| CAS Number | 54739-18-3 | |
| SMILES | COCCCC\C(=N/OCCN)C1=CC=C(C=C1)C(F)(F)F | |
| External Links | ||
| DRUGBANK | DB00176 | |
| T3DB | T3D2705 | |
| PubChem Compound | 3404 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.2 | - | 3.2 | - | DRUGBANK |
| Melting Point | 120.75 | ℃ | 120-121.5 | ℃ | Welle, H.B.A. and Claassen, V.; U.S. Patent 4,085,225; April 18, 1978; assigned to U.S. Phillips Corp. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 53.0 | % | 53.0 | % | DRUGBANK | |
| Clearance | 1.9 | L/h/kg | 31.95 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 25.0 | L/kg | 25.0 | L/kg | DRUGBANK | Volume of Distribution | 23.5 | L/kg | 23.5 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 15.6 | h | 15.6 | h | DRUGBANK | Half-life | 12.5 | h | 12.5 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 94.0 | % | 94 | % | Urinary excretion; PO, oral; | DRUGBANK | Eliminate Route | 2.0 | % | ~2 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 0 | % | ~77-80 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1