Basic Information
| Drug ID | DDPD00165 |
|
| Drug Name | Pyridoxine | |
| Molecular Weight | 169.1778 | |
| Molecular Formula | C8H11NO3 | |
| CAS Number | 65-23-6 | |
| SMILES | CC1=C(O)C(CO)=C(CO)C=N1 | |
| External Links | ||
| DRUGBANK | DB00165 | |
| T3DB | T3D2701 | |
| PubChem Compound | 1054 | |
| PDR | 2705 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.77 | - | -0.77 | - | SANGSTER (1993) |
| Melting Point | 160.5 | ℃ | 159-162 | ℃ | PhysProp |
| Water Solubility | 220000.0 | mg/L | 220000 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 5.5 | h | 5.5 | h | PO, oral; | DRUGBANK |
| Half-life | 420.0 | h | 15-20 | day | adults; | DRUGBANK |
| Toxicity LD50 | 4000.0 | mg/kg | 4.0 | g/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 4000.0 | mg/kg | 4.0 | g/kg | PO, oral; Rattus, Rat; | T3DB |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for neonates | 500.0 | mg | 500 | mg | intravenous injection, IV | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for neonates | 70.0 | mg/kg/dose | 70 | mg/kg/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for neonates | 5.0 | g/dose | 5 | g/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for neonates | 20000.0 | mg | 20 | g | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 60.0 | mg/day | 60 | mg/day | PO, oral | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for infants | 70.0 | mg/kg/dose | 70 | mg/kg/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 5.0 | g/dose | 5 | g/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 20.0 | g | 20 | g | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 40.0 | mg/day | 40 | mg/day | PO, oral | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for infants | 70.0 | mg/kg/dose | 70 | mg/kg/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 5.0 | g/dose | 5 | g/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 20.0 | g | 20 | g | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 30.0 | mg/day | 30 | mg/day | PO, oral | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for infants | 500.0 | mg | 500 | mg | IM,intramuscular injection | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for infants | 70.0 | mg/kg/dose | 70 | mg/kg/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 5.0 | g/dose | 5 | g/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for infants | 20.0 | g | 20 | g | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for children | 80.0 | mg/day | 80 | mg/day | PO, oral | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for children | 70.0 | mg/kg/dose | 70 | mg/kg/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for children | 5000.0 | mg/dose | 5 | g/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for children | 20000.0 | mg | 20 | g | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for children | 60.0 | mg/day | 60 | mg/day | PO, oral | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for children | 70.0 | mg/kg/dose | 70 | mg/kg/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for children | 5000.0 | mg/dose | 5 | g/dose | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for children | 20000.0 | mg | 20 | g | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR | |
| Max dose for adolescents | 100.0 | mg/day | 100 | mg/day | PO, oral | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
| Max dose for geriatric | 100.0 | mg/day | 100 | mg/day | PO, oral | Pyridoxine Hydrochloride | pyridoxine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1