潘建波教授

重庆医科大学生命科学研究院,特聘教授,博士生导师

教育经历:

2005-2009年:厦门大学,学士
2009-2014年:厦门大学,化学生物学博士,方向生物信息学
2014年-2020年:美国约翰霍普金斯大学医学院,生物信息学博士后
2020年加入重庆医科大学生命科学研究院,任特聘教授

研究方向:

1. 生物信息学辅助药物基因组学研究;
2. 癌症组学数据分析以及多组学整合研究;
3. 生物信息学数据库和分析工具的开发;
4. 基于蛋白芯片的肿瘤自身抗体标志物的发现与验证。

E-mail:panjianbo@cqmu.edu.cn

Selected Publications

( 注:*为共同一作 )

1. Huang C*, Chen L*, Savage SR*, Eguez RV, Dou Y, Li Y, da Veiga Leprevost F, Jaehnig EJ, Lei JT, Wen B, Schnaubelt M, Krug K, Song X, Cieślik M, Chang HY, Wyczalkowski MA, Li K, Colaprico A, Li QK, Clark DJ, Hu Y, Cao L, Pan JB, et al. Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma[J]. Cancer cell, 2021, 39(3): 361-379. e16.

2. Zhou Y*, Lih T M*, Pan JB, et al. Proteomic signatures of 16 major types of human cancer reveal universal and cancer-type-specific proteins for the identification of potential therapeutic targets[J]. Journal of hematology & oncology, 2020, 13(1): 1-15.

3. Pan JB*, Hu Y*, Sun S*, et al. Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer[J]. Nature communications, 2020, 11(1): 1-13.

4. Pan JB*, Yu L*, Wu Q*, et al. Integration of IgA and IgG Autoantigens Improves Performance of Biomarker Panels for Early Diagnosis of Lung Cancer[J]. Molecular & Cellular Proteomics, 2020, 19(3): 490-500.

5. Hu Y*, Pan JB*, Shah P*, et al. Integrated proteomic and glycoproteomic characterization of human high-grade serous ovarian carcinoma[J]. Cell reports, 2020, 33(3): 108276.

6. DJ*, Dhanasekaran SM*, Petralia F*, Pan JB*, Song X*, Hu Y*, da Veiga Leprevost F*, Reva B*, Lih TM*, Chang HY, Ma W, Huang C, Ricketts CJ, Chen L, Krek A, Li Y, Rykunov D, Li QK, Chen LS, Ozbek U, Vasaikar S, Wu Y, Yoo S, Chowdhury S, Wyczalkowski MA, Ji J, Schnaubelt M, Kong A, Sethuraman S, Avtonomov DM, Ao M, Colaprico A, Cao S, Cho KC, Kalayci S, Ma S, Liu W, Ruggles K, Calinawan A, Gümüş ZH, Geiszler D, Kawaler E, Teo GC, Wen B, Zhang Y, Keegan S, Li K, Chen F, Edwards N, Pierorazio PM, Chen XS, Pavlovich CP, Hakimi AA, Brominski G, Hsieh JJ, Antczak A, Omelchenko T, Lubinski J, Wiznerowicz M, Linehan WM, Kinsinger CR, Thiagarajan M, Boja ES, Mesri M, Hiltke T, Robles AI, Rodriguez H, Qian J, Fenyö D, Zhang B, Ding L, Schadt E, Chinnaiyan AM, Zhang Z, Omenn GS, Cieslik M, Chan DW, Nesvizhskii AI, Wang P, Zhang H; Clinical Proteomic Tumor Analysis Consortium. Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma. Cell. 2019, 179(4): 964-983.

7. Pan JB*, Zheng QZ*, Li Y*, et al. Discovery and validation of a serologic autoantibody panel for early diagnosis of esophageal squamous cell carcinoma[J]. Cancer Epidemiology and Prevention Biomarkers, 2019, 28(9): 1454-1460.

8. Zhang H*, Pan JB*, Wu X, et al. Large-scale target identification of herbal medicine using a reverse docking approach[J]. ACS omega, 2019, 4(6): 9710-9719.

9. Song G*, Rho H S*, Pan JB*, et al. Multiplexed biomarker panels discriminate Zika and Dengue virus infection in humans[J]. Molecular & Cellular Proteomics, 2018, 17(2): 349-356.

10. Song G*, Lee E M*, Pan JB*, et al. An Integrated Systems Biology Approach Identifies the Proteasome as a Critical Host Machinery for ZIKV and DENV Replication[J]. bioRxiv, 2020.

11. Pan JB, Liu S, Zhu H, Qian J. AAgMarker 1.0: a resource of serological autoantigen biomarkers for clinical diagnosis and prognosis of various human diseases. Nucleic Acids Research. 2018; 46: D886–D893.

12. Pan JB*, Song G*, Chen D*, et al. Identification of serological biomarkers for early diagnosis of lung cancer using a protein array-based approach[J]. Molecular & Cellular Proteomics, 2017, 16(12): 2069-2078.

13. Yoon K J, Song G, Qian X, Pan JB, et al. Zika-virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins[J]. Cell stem cell, 2017, 21(3): 349-358. e6.

14. Huang Y*, Pan JB*, Chen D, et al. Identification and functional analysis of differentially expressed genes in poorly differentiated hepatocellular carcinoma using RNA-seq[J]. Oncotarget, 2017, 8(22): 35973.

15. Hu C J*, Pan JB*, Song G, et al. Identification of novel biomarkers for Behcet disease diagnosis using human proteome microarray approach[J]. Molecular & Cellular Proteomics, 2017, 16(2): 147-156.

16. Pan JB*, Liu S*, Farkas M, et al. Serum molecular signature for proliferative diabetic retinopathy in Saudi patients with type 2 diabetes[J]. Molecular vision, 2016, 22: 636.

17. Qin Y*, Pan JB*, Cai M, et al. Pattern genes suggest functional connectivity of organs[J]. Scientific reports, 2016, 6(1): 1-7.

18. Zhang HP*, Pan JB*, Zhang C, et al. Network understanding of herb medicine via rapid identification of ingredient-target interactions[J]. Scientific reports, 2014, 4(1): 1-8.

19. Pan JB*, Ji N*, Pan W, et al. High-throughput identification of off-targets for the mechanistic study of severe adverse drug reactions induced by analgesics[J]. Toxicology and applied pharmacology, 2014, 274(1): 24-34.

20. Pan JB, Hu SC, Shi D, et al. PaGenBase: a pattern gene database for the global and dynamic understanding of gene function[J]. PloS one, 2013, 8(12): e80747.

21. Pan JB, Hu SC, Wang H, et al. PaGeFinder: quantitative identification of spatiotemporal pattern genes[J]. Bioinformatics, 2012, 28(11): 1544-1545.

22. Wu L, Huang T, Yang L, Pan JB, et al. Sensitive and selective bacterial detection using tetracysteine‐tagged phages in conjunction with biarsenical dye[J]. Angewandte Chemie International Edition, 2011, 50(26): 5873-5877.