Perturbation information

Perturbed Gene Akt1 LocusTag - Type of Gene protein-coding
Description thymoma viral proto-oncogene 1
Edit Type mutation
Organism Mus_musculus
Tissue Type colon
Characteristics disease;genotype:Trp53[delta]IECAktE17K
Control | Case GSM4043453;GSM4043454;GSM4043457;GSM4043458 GSM4043455;GSM4043456;GSM4043459;GSM4043460
Data Source GEO
Accession GSE136257
Data Type RNA-Seq
Pubmed ID 32749453

Altered phenotypes

Phenotype resemble the human mesenchymal colorectal cancer subtype (CMS4), which is characterized by the poorest survival rate among the four consensus molecular subtype (CMS)

Differential genes

Gene Name AveExpr Control AveExpr Case Log2FC P-value Adjusted P-value Regulation Boxplot

Volcano plot

Heatmap

Enriched regulations/functions/pathways


TF Regulation Gene Ratio Bg Ratio P-value Adjusted P-value Enriched Gene Count

ID Terms Size ES NES P-value Adjusted P-value Plot


Differential cell type markers

Cell Type Source Regulation Gene Ratio Bg Ratio Hypergeometric P-value Adjusted P-value Marker Gene